lymphocyte subpopulations and cell-mediated immunity in multiple sclerosis in iran

thirty seven randomly selected patients suffering from multiple s c l e r os i s (ms) (17 males and 20 females)and 30 healthy control subjects were studied for the lymphocyte subpopulations and ce l l -medi a t e d immunity.we obs e r ved a decrease of the total t-cells and an increase of a ctive t-lymphocytes and b ce l l s , in ms p at i ent s as compared t o normal controls. the inability of ms lymphocytes t o measles antigen by lmt or ltt in our e xpe r i me nt s could be due t o t-lymphocyte dysfunction.